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STRESSOR Metformin OD-too much of drug Interferes with normal cell function CELL INJURY lack of O2 and unable to make ATP ADAPTION switches to anaerobic metabolism COUNTERATTACK GSR RAA   HEALING anaerobic metabolism to prevent cell death/injury S/S unconscious drowsy pain response hypotension high pulse high respirations low blood pH COMPLICATIONS inability to make ATP->(lack of O2)-> anaerobic metabolism -> decrease in bllod pH (metabolic acidosis)-> lactic buildup-> lactic acidosis